I'm Thomas O'Brien. I live on the Mississippi and make research tools.

Lately I've been building things like Streams, an app that researches for you. Every night, deep in the digital backcountry, we look for gems you haven't found.

I cofounded Glif and built apps for Protocol Labs and ConsenSys.

I helped write Machine learning for hypothesis generation in biology and medicine and built the domain translator that accompanies it.